Tracking antigen-specific T cell response to cancer immunotherapy

Name: Tracking antigen-specific T cell response to cancer immunotherapy
Published: 2024-11-29T10:19:00+00:00
License: https://creativecommons.org/licenses/by/4.0/
Keywords: melanoma antigen peptides

dataset

posted on 2024-11-29, 10:19 authored by Tatiana NakonechnayaTatiana Nakonechnaya

peptide_vaccination.zip contains TCRb clonotypes for mices which was vaccinated by 14 peptides. Samples are describes in metadata : SupplementTable1_metadata.xlsx. Infromation about peptides contains in Table_1_peptides.xlsx.
SupplementTable2_SamplesClusters : matrix, presentes cuumulative frequency of each cluster between samples.
SupplementTable3_clusters : produced dataset of helper T cells (Th) TCR beta CDR3s specific to B16 melanoma neoantigens in the I-Ab pMHCII context
CTLA4_treatment.zip : dataset with TCRb clonotypes of dLNs and ndLNs of CTLA-4 treated and control mice, metadata inside.

Tracking antigen-specific T cell response to cancer immunotherapy

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