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Top 5 activated and top 5 repressed pathways based on p-value in RHD compared to ARF obtained using EnrichR.
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posted on 2023-04-05, 17:42 authored by Ranjitha Guttapadu, Nandini Prakash, Alka M, Ritika Chatterjee, Mahantesh S, Jayranganath M, Usha MK Sastry, Jayshree Rudrapatna Subramanyam, Dipshikha Chakravortty, Kalpana S. R, Nagasuma ChandraTop 5 activated and top 5 repressed pathways based on p-value in RHD compared to ARF obtained using EnrichR.
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significantly raised neutrophilrheumatic heart diseaseprequel disease statenetwork analysis approachlow income dueinform future diagnosticsinflammatory process typicalimproving patient caregenetic basis commoneffective diagnostic techniquesdeveloping predictive biomarkerscollected blood transcriptomeschemokine signaling pathwayaffect developing countriesacute rheumatic feverwide molecular insightswide variationslevel insightstryptophan metabolismtherapeutic strategiessubnetwork comprisingprofiling systempossible causespilot studyperturbed pathwayslymphocyte ratiointegrated transcriptomehost processesgain systemactivated neutrophils
