TGFβ increases TGFBR1 (ALK5) and decreases ACVRL1 (ALK1) in human BMSC pellets.
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posted on 2015-12-31, 09:15 authored by Laurie M. G. de Kroon, Roberto Narcisi, Esmeralda N. Blaney Davidson, Mairéad A. Cleary, Henk M. van Beuningen, Wendy J. L. M. Koevoet, Gerjo J. V. M. van Osch, Peter M. van der KraanTGFβ increases TGFBR1 (ALK5) and decreases ACVRL1 (ALK1) in human BMSC pellets.
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cartilage matrix formationreceptors ALK 5Conclusion ALK 5collagen type IIActivin Receptor-Like Kinase Receptors ALK 5ALK 1 gene expressionTGF β receptorsHuman Bone Marrow-Derived Mesenchymal Stem Cells Introduction Bone marrow-derived mesenchymalmodulates ALK 5serum-free chondrogenic mediumBMSCALK 1ALK 5cartilage tissue-producing chondrocytesALK 1. Results ALK 5chondrogenic differentiationcaALK 1 overexpressionALK 1 receptorMethods ALK 5caALK 1. ExpressioncaALK 5TGF β-induced chondrogenesisActivin receptor-Like Kinase
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