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TGFβ increases <i>TGFBR1</i> (ALK5) and decreases <i>ACVRL1</i> (ALK1) in human BMSC pellets.

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posted on 2015-12-31, 09:15 authored by Laurie M. G. de Kroon, Roberto Narcisi, Esmeralda N. Blaney Davidson, Mairéad A. Cleary, Henk M. van Beuningen, Wendy J. L. M. Koevoet, Gerjo J. V. M. van Osch, Peter M. van der Kraan
<p>TGFβ increases <i>TGFBR1</i> (ALK5) and decreases <i>ACVRL1</i> (ALK1) in human BMSC pellets.</p>

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  1. 1.
    DOI - Is supplement to Activin Receptor-Like Kinase Receptors ALK5 and ALK1 Are Both Required for TGFβ-Induced Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells

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    cartilage matrix formationreceptors ALK 5Conclusion ALK 5collagen type IIActivin Receptor-Like Kinase Receptors ALK 5ALK 1 gene expressionTGF β receptorsHuman Bone Marrow-Derived Mesenchymal Stem Cells Introduction Bone marrow-derived mesenchymalmodulates ALK 5serum-free chondrogenic mediumBMSCALK 1ALK 5cartilage tissue-producing chondrocytesALK 1. Results ALK 5chondrogenic differentiationcaALK 1 overexpressionALK 1 receptorMethods ALK 5caALK 1. ExpressioncaALK 5TGF β-induced chondrogenesisActivin receptor-Like Kinase

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