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DGRP_data_out.csv (1.88 kB)

Susceptibility of different Drosophila melanogaster DGRP lines to three sigma viruses.

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posted on 2018-11-19, 13:32 authored by Ben LongdonBen Longdon
We infected 32 lines from the Drosophila Genetic Reference Panel (DGRP) that were susceptible for both p62 (Ref2P) and CHKov (n=11 lines), were resistant for CHKov only (n=13 lines), or were resistant for both genes (n=8 lines) with DMelSV, DAffSV and DObsSV. No lines in the panel were resistant for p62 only. We infected a mean of 18 flies per line (range = 3-22).


ref2p_chkov coding as follows
("0_0", "0_1", "1_1") == ("Both sus", "Ref2P susceptible CHKov resistant", "Both resistant")

Funding

Natural Environment Research Council grant (NE/L004232/1 http://www.nerc.ac.uk/); European Research Council grant (281668, DrosophilaInfection, http://erc.europa.eu/); Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (Grant Number 109356/Z/15/Z).

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