Table S1 Summary of 61 top hits that passed the initial selection criteria (proof).xlsx (668.66 kB)View fileThis item contains files with download restrictions
DATASET
Table S2 Cell death-imaging analysis of 32 core-set small molecules (proof).xlsx (28.2 kB)View fileThis item contains files with download restrictions
DATASET
Table S3 Protection of WI-38 cells from the heavy metal CdCl2 by small molecules (proof).xlsx (20.49 kB)View fileThis item contains files with download restrictions
DATASET
Table S4 Effects of small molecules on ATP level and DNA damage-associated markers (proof).xlsx (112.56 kB)View fileThis item contains files with download restrictions
DATASET
Table S5A List of significant genes identified by RNA-seq for cells treated with Gr-4D (proof).xlsx (454.34 kB)View fileThis item contains files with download restrictions
DATASET
Table S5B List of significant genes identified by microarray for cells treated with others (proof).xlsx (1.05 MB)View fileThis item contains files with download restrictions
DATASET
Table S6 Summary of pathway analysis results for RNA-seq of cells treated with small molecules (proof).xlsx (46.57 kB)View fileThis item contains files with download restrictions
DATASET
Table S7 Potential mTOR inhibition by certain small molecules (proof).xlsx (9.9 kB)View fileThis item contains files with download restrictions
DATASET
Table S8 Effects of small molecules on C. elegansΓÇÖ lifespan and H2O2-resistance (proof).xlsx (19.62 kB)View fileThis item contains files with download restrictions
DATASET
Table S9 Potential targets for small molecules (proof).xlsx (131.26 kB)View fileThis item contains files with download restrictions
DOCUMENT
Small molecule screen manuscript Supplemental Text_proof.pdf (293.86 kB)View fileThis item contains files with download restrictions
Version 2 2020-01-29, 13:27Version 2 2020-01-29, 13:27
Version 1 2019-12-26, 18:50Version 1 2019-12-26, 18:50
dataset
posted on 2020-01-29, 13:27authored byPeichuan ZhangPeichuan Zhang, Yuying Zhai, James Cregg, Kenny Kean-Hooi Ang, Michelle Arkin, Cynthia Kenyon
Revised supplemental text, supplemental figures S1 to S10, and supplemental tables S1 to S9 for manuscript G3/2019/400618
History
Article title
Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules that Affect Aging Pathways and Extend Caenorhabditis elegans’ Lifespan