Table 1.xls (5.5 kB)
Summary of simulation study results: Mean squared errors (MSE) and coverage of the 95% confidence interval for the residual and doubly-ranked stratification method in each scenario.
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posted on 2023-06-30, 17:33 authored by Haodong Tian, Amy M. Mason, Cunhao Liu, Stephen BurgessMSE is calculated as an average across estimates in all 10 strata, and the results are averaged across 1000 datasets per scenario.
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systolic blood pressuresimulation study indicatesstrong parametric assumptionsrelaxing parametric assumptionsstandard mendelian randomizationdifferent average levelsxlink "> nonobtain unbiased stratumlinear mendelian randomizationinstrumental variable assumptionsnew stratification methodinstrumental variablestratification assumptionsstandard implementationhigher levelsresidual methodranked methodtruncated ),substantial biasstratification approachspecific estimatesoutcome usingmisleading estimatesfound evidencecausal relationshipalcohol intake
