Sample sizes and test likelihoods for each de novo comparison dataset.
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posted on 2023-07-07, 17:45 authored by Christopher J. Adams, Mitchell Conery, Benjamin J. Auerbach, Shane T. Jensen, Iain Mathieson, Benjamin F. VoightSample sizes and test likelihoods for each de novo comparison dataset.
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typical sample sizeslearning inspired strategyde novo comparing model concordancemer context windowssparse data settingmodeling germline mutationsreturn parsimonious modelsgenerate parsimonious modelsmutation rates acrossdiv >< pcontext based probabilitiescalibrated posterior distributionsmutation rate modelsposterior distributionsgermline mutationmutation probabilitiesshared contextestimated ratesdata sparsitypolymorphism probabilitiesprevious modelspolymorphism modelsmodels existvariant agescales computationallyquantified uncertaintyinferences derivedidentifying differencesheterogeneous effectgenetic variationfacilitate comparisondemonstrate applicationdemographic historycontinental populationsautomatically adaptsappropriately regularizesadaptive metropolis
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