STING FSR raw data.
dataset
posted on 2025-02-25, 18:47 authored by Thomas E. Angel, Zhuo Chen, Ahmed Moghieb, Sze-Ling Ng, Allison M. Beal, Carol Capriotti, Leonard Azzarano, Debra Comroe, Michael Adam, Patrick Moore, Bao Hoang, Kelly Blough, Joanne Kuziw, Joshi M. Ramanjulu, G. Scott PesiridisSpreadsheets containing raw data values for STING protein abundance, kinetics of fractional STING synthesis, and fold changes in RNA expression.
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using metabolic labelingsle linked pathophysiologydeuterium oxide pairedappears inversely proportionalunderstanding sting ’sting receptor levelsincreased sting levelstrex1 d18n mutationinflamed mice carryingdiv >< pd18n sting protein halfsting protein abundanceprotein degradationwt miceinflamed trex1valuable componenttissue specifictarget dispositionskeletal muscleshortest halfrelative increasequantitative modelingoverall kineticsmodeling pharmacologylymph nodelongest halfinterferon genesinflammatory diseaseshuman acardigoutiéres syndromeessential componentdrugs targetingdose frequencydisease tissuedependent modelaccurate determination4 days24 days
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