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posted on 2016-07-19, 14:37 authored by Bonnie K. Harrington, Heather L. Gardner, Raquel Izumi, Ahmed Hamdy, Wayne Rothbaum, Kevin R. Coombes, Todd Covey, Allard Kaptein, Michael Gulrajani, Bart Van Lith, Cecile Krejsa, Christopher C. Coss, Duncan S. Russell, Xiaoli Zhang, Bridget K. Urie, Cheryl A. London, John C. Byrd, Amy J. Johnson, William C. KisseberthPatient Demographics.
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weight lossB-cell lymphoma2 anorexia22.5 daysresponse rateB-cell lymphoma cell linePreclinical Evaluationgrade 1B-cell malignancyacalabrutinib potentlylymphoma cellsCanine ModelsCLBL 1 cellstarget selectivityBTK activityB-cell lymphoma patientsACPDLBCLNovel BTK Inhibitor Acalabrutinib24 hoursBruton agammaglobulinemia tyrosine kinaseORRnon-Hodgkin lymphomasecond-generation inhibitorexhibits activityNHLClinical benefitB-Cell Non-Hodgkin Lymphoma AcalabrutinibPFS
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