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Number of tdT+ cells in the cortex of Nkx2.1-cKO mice at E14.5.

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posted on 2021-03-19, 17:36 authored by Sathish Venkataramanappa, Dagmar Schütz, Friederike Saaber, Praveen Ashok Kumar, Philipp Abe, Stefan Schulz, Ralf Stumm

The table shows the number of tdT+ cells in the cortex of Nkx2.1-cKO (cKO) and control mice at E14.5. Data are presented in percent of the control mean. The quantification area is indicated by an arrowhead in Fig 5A.

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The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons
PLOS GeneticsPLOS Genetics

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progenitorsGABAergic neuronsGABAergic neurons Biallelic mutationsNkx 2DONSONmicrocephaly gene Donsonreplication fork protection factorpostnatal expression decreaseneocortexCre-mediated Donson deletion

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