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Non-invasive prenatal diagnosis of genetic diseases in early pregnancy using mass spectrometry

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posted on 2025-05-25, 11:24 authored by Feng ZhouFeng Zhou, Qinghe XIng, Tongchuan Li, Xiangdong Kong, Lin He, Ting Wang, Zhenhua Zhao, Lanlan Zhang, Xin Li, Yimeng Qiao, Fei ZhuFei Zhu

This dataset contains raw mass spectrometry (MS) data, including MS1 and MS/MS spectra, supporting the non-invasive prenatal diagnosis of genetic diseases in early pregnancy. The data were acquired using a SCIEX TripleTOF® 4600 mass spectrometer coupled with the DuoSpray™ Turbo V ion source operated in negative ion mode. The raw files are in WIFF format and can be viewed and analyzed using PeakView software. A detailed description of the files used for each figure is provided in the accompanying Readme.xlsx file.

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