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Neutral Dinuclear Copper(I)-NHC Complexes: Synthesis and Application in the Hydrosilylation of Ketones

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posted on 2016-12-06, 13:37 authored by Michael Trose, Faïma Lazreg, Tao Chang, Fady Nahra, David B. Cordes, Alexandra M. Z. Slawin, Catherine S. J. Cazin
The synthesis of a class of highly stable neutral dinuclear Cu­(I)-NHC complexes using 1,2,4-triazole as a bridging ligand is described. Various NHCs were used to generate a library of [Cu­(μ-trz)­(NHC)]2 complexes. Interestingly, [Cu­(μ-trz)­(IPr)]2 was found to be highly active in the hydrosilylation of ketones, without the need for an external base or any other additive. A wide range of aryl and alkyl ketones, as well as sterically hindered ketones, was successfully reduced to alcohols using the lowest catalyst loading reported to date.