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posted on 2017-02-03, 16:23authored byBenjamin DermanBenjamin Derman, Jason N Macklis, Mohammed S Azeem, Selina Sayidine, Sanjib Basu, Marta Batus, Fatema Esmail, Jeffrey A Borgia, Philip Bonomi, Mary J Fidler
There is emerging evidence showing a significant relationship between
overall survival (OS) in non-small cell lung cancer NSCLC patients and weight
change during chemotherapy or chemoradiation. A high neutrophil/lymphocyte
ratio (NLR) at baseline and at follow-up is associated with shorter survival in
cancer patients and may be a surrogate for ongoing inflammation, implicated in cancer
cachexia and tumor progression. The data presented here was collected to explore
potential relationships between OS, serial weights, and serial NLRs in advanced
NSCLC patients receiving chemotherapy.