Mutations in the TLD-resistant evolved isolate in the MDS42 background.
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posted on 2022-10-24, 17:31 authored by Alexandra Ketcham, Peter L. Freddolino, Saeed TavazoieMutations in the TLD-resistant evolved isolate in the MDS42 background.
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underlying killing mechanismpreviously unknown rolepreviously implicated pathwaysdiv >< pdiscovering novel genesrobust early eventenigmatic process knowncommon mechanistic stepescherichia coli intracellular acidification maycoli mechanistic understandingdeath processcausal eventintracellular phintracellular acidificatione unbiased approachesthymineless deathsystematically determinestudies revealedstill lackregulatory underpinningsdiverse setdiverse antimicrobialdespite decadescytoplasmic phcausal sequencebactericidal effectsantineoplastic drugsantibiotic gentamicinalso observe
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