Data: Improving the Performance of J-modulated ADEQUATE Experiments Through Homonuclear Decoupling and Non-Uniform Sampling

<p>Homonuclear ¹³C-¹³C couplings at natural abundance can be measured using the <em>J</em>-modulated ADEQUATE experiment. To somewhat ameliorate F1 digitization requirements, a scaling factor was incorporated into the original pulse sequence. Non-Uniform Sampling (NUS) provides an obvious avenue to further facilitate the acquisition of ¹<em>J</em>_CC and ⁿ<em>J</em>_CC homonuclear coupling constant data. We introduce homonuclear decoupling (HD) analogous to that described for the 1,1- and 1,n-HD-ADEQUATE experiments and evaluate the combination of NUS and homonuclear decoupling on the acquisition of both ¹<em>J</em>_CC and ⁿ<em>J</em>_CC homonuclear ¹³C-¹³C coupling constants using ibuprofen as a model compound.</p>