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Idesolide:  A New Spiro Compound from Idesia polycarpa

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posted on 2005-07-21, 00:00 authored by Seung Hyun Kim, Sang Hyun Sung, Soo Young Choi, Young Keun Chung, Jinwoong Kim, Young Choong Kim
Idesolide, a new spiro compound possessing tetrahydrobenzodioxole structure, was isolated from the fruits of Idesia polycarpa Maxim. Its structure was established by NMR and MS spectroscopic analysis with single-crystal X-ray experiments. Idesolide significantly reduced nitric oxide production induced by lipopolysaccharide in BV2 microglial cells.