Harnessing Repetition-Rate-Dependent Microbubble Chains for Precision Microflow Control in Laser-Induced Microfluidic Chips: Original Experimental Data and Analysis

<p dir="ltr">This dataset comprehensively supports the findings of the research article entitled "Harnessing Repetition-Rate-Dependent Microbubble Chains for Precision Microflow Control in Laser-Induced Microfluidic Chips." The study introduces a novel, programmable microflow control technique utilizing the collective dynamics of femtosecond laser-induced microbubble (FLIMB) chains, governed solely by the laser repetition rate. <br>Research Background and Significance:<br>Precise flow control at the microscale without mechanical components remains a significant challenge in microfluidics. This work demonstrates that the rising velocity of FLIMB chains follows a robust logarithmic scaling law with respect to the laser repetition rate (1-1000 Hz). It identifies two distinct, reconfigurable flow regimes: a microbubble "annihilation" mode at low rates (< 5 Hz) and a stable, high-speed "spindle-shaped" convective flow at high rates, ideal for applications such as micromixing and particle manipulation. <br><b>Data Content and Structure: </b><br>The dataset contains original experimental measurements, processed data, and fitting parameters necessary to reproduce the figures and conclusions of the associated study. Key components include: </p><ul><li>Raw and processed data​ for microbubble diameter, rising velocity, and count across different laser repetition rates and liquid media (water, ethanol, methanol). </li><li>Fitting parameters​ for the logarithmic relationship (v = a ln(f + c) + b) between velocity (v) and repetition rate (f), including uncertainties and coefficients of determination (R²). </li><li>High-resolution image data​ used for quantitative analysis via particle tracking and image processing. </li></ul><p dir="ltr"><b>Experimental Methodology: </b><br>Data were generated using a Ti:Sapphire femtosecond laser amplifier (800 nm center wavelength, 50 fs pulse width). The laser was focused into a quartz cuvette containing the liquid samples. Microbubble behavior was recorded with a digital camera (Nikon D700). The dataset reflects systematic variation of key parameters:</p><ul><li> Laser Repetition Rate:​ 1 - 1000 Hz </li><li>Pulse Energy:​ 22.5 μJ, 213 μJ, 2187 μJ </li><li>Liquid Media:​ Distilled water, ethanol, methanol (purity ≥ 99.5%) </li></ul><p dir="ltr"><b>Data File Organization and Usage: </b></p><p dir="ltr">The dataset is organized into clear categories for ease of reuse. The file README.txtprovides a detailed guide to the dataset's structure, file naming conventions, and column definitions for all tabular data (e.g., .csvfiles). This facilitates replication of the analysis, secondary research, and integration into computational models. The file Figures.pdfcontains the assembled result figures corresponding to those in the main text. </p><p dir="ltr"><b>Reusability and Value: </b></p><p dir="ltr">This dataset adheres to the FAIR (Findable, Accessible, Interoperable, Reusable) principles. It provides a complete record of the experimental results, enabling: </p><ol><li>Independent verification​ of the reported logarithmic scaling law and flow regimes. </li><li>Further analysis​ and modeling of laser-induced microbubble dynamics. </li><li>Benchmarking​ for future studies in optofluidics and active microflow control. </li><li>Design parameters​ for developing microfluidic devices utilizing this optical control mechanism. </li></ol><p dir="ltr">By providing both raw and analyzed data, this dataset serves as a valuable resource for researchers in microfluidics, laser-material interactions, and lab-on-a-chip technology.</p>