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Gene ontology (GO) enrichment analysis results for significantly upregulated genes at all time points.

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posted on 2022-12-01, 18:50 authored by Stuart Meier, James A. Seddon, Elizna Maasdorp, Léanie Kleynhans, Nelita du Plessis, Andre G. Loxton, Stephanus T. Malherbe, Daniel E. Zak, Ethan Thompson, Fergal J. Duffy, Stefan H. E. Kaufmann, Tom H. M. Ottenhoff, Thomas J. Scriba, Sara Suliman, Jayne S. Sutherland, Jill Winter, Helena Kuivaniemi, Gerhard Walzl, Gerard Tromp

The analysis was performed using the topGO R Bioconductor package. The statistical metrics presented for each process include: the total number of genes annotated to the process (Total annotated), the number of genes that were significantly up (N up) -regulated, the percent of total annotated that were up-regulated (% Up) and the number that were expected by chance (Expected). The uncorrected Fisher’s exact test p-value (Pvalue) and overall rank for over-representation of the GO term in the set using both the classic and weight01 (W1) algorithms are presented.

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