From Nitrobenzenes to Substituted Tetrahydroquinolines in a Single Step by a Domino Reduction/Imine Formation/Aza-Diels–Alder Reaction
datasetposted on 20.02.2015 by Hans-Georg Imrich, Jürgen Conrad, Denis Bubrin, Uwe Beifuss
Datasets usually provide raw data for analysis. This raw data often comes in spreadsheet form, but can be any collection of data, on which analysis can be performed.
The three-component reaction between a nitrobenzene, an aldehyde, and a dienophile in the presence of iron powder as a reductant and montmorillonite K10 as a catalyst in aqueous citric acid delivers the products of an aza-Diels–Alder (Povarov) reaction with high endo-selectivity and yields up to 99%.