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Evaluation of treatments human rabies post-exposure prophylaxis in a city of Paraíba

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posted on 13.06.2018, 02:48 by Joyce Pereira de Azevedo, Jéssica Cardoso Pessoa de Oliveira, Poliana de Araújo Palmeira, Nirley Vercelly Lopes Formiga, Vanessa Santos de Arruda Barbosa

Abstract Introduction Rabies is a zoonotic infection transmitted by virus inoculation through saliva and secretions of infected animals. The study evaluated the conduct of the post-exposure care of human rabies, between 2006 and 2013 in Cuité-Paraíba. Method: We evaluated 184 records included in the SINAN (Sistema de Informações de Agravos de Notificação). We used the chi-square test and calculated the prevalence ratio (PR) and confidence intervals (CI). Results Analysis show that 53.3% of the accidents happened with females, and 39.1% were between 20 and 59 years old. Bite was the most common assault (72.3%) and 41.5% of the aggressions resulted in severe lesions. Dogs were responsible for 66.1% of the aggressions. Attacks were also committed by cats, primates and foxes. There was association between the aggressor species and sex of individuals (p=0.019). We observed a higher frequency of aggressions by dogs in men (PR=1.587, CI=1.039-2.422) and by cats in women (PR=1.415, CI = 1.080 to 1.855). There was an association between aggression by dogs in the lower limbs (p=0.008, PR=2.065, CI=1.138-3.749) and by cats on hand/foot (p=0.001, PR=2.045, CI=1.340-3.123). Most of the care (59.8%) consisted of observation + vaccine and 59.2% followed the Ministry of Health protocol. Conclusion It is essential to improve methods for prescribing and recording of injuries treatment.