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Effects of methanolic extract from <i>Diospyros malabarica</i> and <i>Gynocardia odorata</i> on liver Total protein, Albumin, Globulin, Total bilirubin, SGOT and SGPT on CCl<sub>4</sub> induced hepatotoxicity in rats.

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posted on 2022-03-21, 17:37 authored by Arabinda Ghosh, Pranjal Sarmah, Harun Patel, Nobendu Mukerjee, Rajbardhan Mishra, Saad Alkahtani, Rajender S. Varma, Debabrat Baishya
<p>Effects of methanolic extract from <i>Diospyros malabarica</i> and <i>Gynocardia odorata</i> on liver Total protein, Albumin, Globulin, Total bilirubin, SGOT and SGPT on CCl<sub>4</sub> induced hepatotoxicity in rats.</p>

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    nonlinear molecular dynamicsmolecular dynamics simulationmajor signaling proteinshplc analysis revealedgene expression profileeventually cause damagediv >< pcytochrome p450 enzymescritical physiological functionsaugmenting bilirubin content89 &# 17753 &# 17748 &# 177gynocardia odorata </diospyros malabarica </silico molecular dockingrevealed high bindinginduced hepatic injuryliver performs numberliver function analysiscauses liver damagequercetin (&# 916hepatotoxic wistar ratscytochrome p450 cyp2e1silico </wistar ratsinduced hepatotoxicityhigh affinityliver leadssubstantial rolestudy highlightssignificant rolesgpt activitypotent inhibitorpossible mechanismplausible affinitymmp2 expressedmmgbsa studiesmechanistic rolehuman systemfruit extractsfree radicalscarbon tetrachloridebetter stability78 kcal

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