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Effect of adjunct oral zinc on primary and secondary outcomes.

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posted on 2025-10-09, 18:20 authored by Nitya Wadhwa, Antara Sinha, Sudha Basnet, Sugandha Arya, Raghvendra Singh, Mamta Jajoo, Ayushi, Dharmendra Sharma, Ajay Kumar, Harish K. Pemde, Varinder Singh, Ram H. Chapagain, Anuradha Govil, Debjani R. Purakayastha, Ganesh P. Shah, Medha Mittal, Laxman P. Shrestha, Harish Chellani, Halvor Sommerfelt, Tor A. Strand, Shinjini Bhatnagar
<p>Effect of adjunct oral zinc on primary and secondary outcomes.</p>

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    specific case definitionsreceive 10 mgfound little evidenceeffective interventions addedcompleted 12 weeksclinical severe infectionanticipated event ratesuniversal trial numbersubsequent 3 monthsreduce sepsis mortalityelemental zinc daily576 infants died153 enrolled infantsstandard antimicrobial therapyyoung infant sepsisxlink "> annuallyzinc arm comparedadjunct zinc therapystandard deviation 00 %) diedadjunct zinc treatmentnepal </ pyoung infantsxlink ">zinc armadjunct treatmentsuspected sepsisp </including sepsiscontrolled trial554 infants6 %)placebo armunderpowered duesouth asiaslight increasesaharan africarecent metarandomly assignedprimary outcomesmedian agemean weightmajor contributorsmain limitationintegrated managementhospital stayfirst monthfebruary 28february 27february 22

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