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Effect of CRH on brain activation in response to colonic distentions.

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posted on 2016-07-22, 07:09 authored by Yukari Tanaka, Motoyori Kanazawa, Michiko Kano, Joe Morishita, Toyohiro Hamaguchi, Lukas Van Oudenhove, Huynh Giao Ly, Patrick Dupont, Jan Tack, Takuhiro Yamaguchi, Kazuhiko Yanai, Manabu Tashiro, Shin Fukudo

Effect of CRH on brain activation in response to colonic distentions.

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Differential Activation in Amygdala and Plasma Noradrenaline during Colorectal Distention by Administration of Corticotropin-Releasing Hormone between Healthy Individuals and Patients with Irritable Bowel Syndrome
PLOS ONEPLOS ONE

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IBS patientsactivationExogenous CRH differentially sensitizes brain regionsACTHserum cortisol secretionPlasma adrenocorticotropic hormonepositron emission tomographyCRH agonists changeIrritable Bowel Syndrome Irritable bowel syndromecolorectal distentionCRH injectionbarostat bag inflationBrain H 2 15 Oright amygdalaplasma noradrenaline levels

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