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EXCEL MODEL WITH WANING FOR POSTING REVISED v.2

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Version 3 2024-01-11, 21:55
Version 2 2023-12-17, 00:52
Version 1 2023-01-19, 20:20
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posted on 2024-01-11, 21:55 authored by David FismanDavid Fisman

This revised version of our earlier mixing model incorporates additional complexity including:


1. Waning immunity.

2. Differential risk and infectivity by prior immune experience.

3. Effects of hybrid immunity.

4. Boosting.

5. Diminished vaccine efficacy to reflect immune evasion with Omicron SARS-CoV-2 variants.

Funding

The research was supported by a grant to DNF from the Canadians Institutes for Health Research (2019 COVID-19 rapid researching funding OV4-170360.

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