Differential Gene Expression

For each organ, pairwise differential expression analysis between different ages with DESeq2. Fold change represents X over Y (so that X>Y if fold change is positive), if the internal naming scheme is X_vs_Y.

Examples of how to load and view results:

# load results

load("MACA_Bulk_deseq2_results.bin")

# list of tissues

ls(results_list_MACA_bulk)

# list of comparisons for Bone

ls(results_list_MACA_bulk$Bone)

# All results: comparison 3 vs 18 for Bone

results_list_MACA_bulk$Bone$`18_vs_3`$resall

# q<0.05 only: comparison 3 vs 18 for Bone

results_list_MACA_bulk$Bone$`18_vs_3`$ressig