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Description of the gold standard datasets [12,38].

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posted on 2023-08-03, 17:34 authored by Hakimeh Khojasteh, Jamshid Pirgazi, Ali Ghanbari Sorkhi

Description of the gold standard datasets [12,38].

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    PLOS ONE

    Categories

    • Pharmacology
    • Biological Sciences not elsewhere classified
    • Information Systems not elsewhere classified
    • Mathematical Sciences not elsewhere classified
    • Science Policy

    Keywords

    wet lab experimentslimiting search spaceimportant challenging taskexperimental results demonstratefusing multiple featuresimbalanced data duedrug discovery reliesdrug chemical compoundsobtain optimal featurestarget interactions baseddiv >< pcomputational methods basedproposed approach srxoptimal featurescomputational methodsstage approachknown interactionsdata balancingexisting methodspredicting drugtarget interactionvarious descriptorsus techniquesource codesecond stagerecent yearsrandom forestprotein targetsprotein sequencespredictive performancepredicting dtisnovel multimany researchersmajor challengemachine learningimproving predictionfp2 fingerprintfirst stagefeature vectorscalled srxbalanced dataset

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