Dataset on the metabolome and the gut microbiota in mice after heatstroke

<p dir="ltr">Heatstroke (HS) can trigger cytokine storm and multiple organ dysfunctions, but its pathophysiological mechanisms are complex and remain incompletely understood. Herein we explored the potential mechanisms on HS-driven inflammatory responses from the perspective of the gut microbiota-metabolite axis. In this dataset, the metabolic profiles of intestinal contents, serum, liver and cortex in mice after HS were analyzed by using an untargeted LC-MS-based metabolomics method. Moreover, the gut microbiota was analyzed via 16S rRNA gene sequencing in the intestinal contents of mice after HS or HS mice after treatment with an arginine-enriched oral inulin hydrogel.</p>