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Dataset 6: Stalk-reactive antibody responses to H3 viruses enhanced by Il-15

dataset
posted on 2017-10-13, 14:11 authored by Junqiong Huang, Shannon P. Hilchey, Jiong WangJiong Wang, Jessica Garigen, Martin ZandMartin Zand
Purified B cells were costimulated with CpG2006, A/Victoria/361/2011 viruses and IL-15. Stalk-reactive IgG in supernatants was detected at day 6. Chimeric molecules cH5/3, cH4/7 and cH5/1 were used for assessing antibodies against H3 stalk, H7 stalk and H1 stalk, respectively. Each symbol and line represents an individual donor. (A) H3 stalk-reactive antibodies. (B) H7 Stalk-reactive antibodies. (C) H1 stalk-reactive antibodies.

Funding

Zunyi Medical University (JH) Visiting Scholar Grant 201408525075, National Institutes of Health - National Institute of Allergy, Immunology, and Infectious Disease Grants AI098112, AI069351, AI109946

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