posted on 2025-02-04, 23:53authored byJustin Daho LeeJustin Daho Lee, Amanda Nguyen, Chelsea E. Gibbs, Zheyu Ruby Jin, Yuxuan Wang, Aida Moghadasi, Sarah J. Wait, Hojun Choi, Kira M. Evitts, Anthony Ascencio, Samantha B Bremner, Shani Zuniga, Vedant Chavan, C. Andrew Williams, Annette Smith, Farid Moussavi-Harami, Michael Regnier, David Baker, David L Mack, Elizabeth Nance, Patrick M BoylePatrick M Boyle, Andre BerndtAndre Berndt
Description:
This dataset contains the code, data, and computational resources used to generate the results presented in the paper “Monitoring in Real-Time and Far-Red Imaging of H₂O₂ Dynamics with Subcellular Resolution.”
Contents:
Conda Environment – Environment configuration to ensure reproducibility.
Data, Visualization, and Detailed Statistics – Raw data and statistical analysis for main and supplementary figures.
ColabFold Prediction Structures – Computationally predicted protein structures.
Analysis Code for Immunofluorescence (IF) Data – Scripts for quantifying nuclear translocation.
Computational Cell-Scale Modeling Code – Simulations for modeling hiPSC-CMs at the cellular level.
This upload provides all necessary materials to reproduce the analysis and visualizations presented in the study.
For any inquiries, please contact:
Justin Daho Lee(justindaholee@gmail.com), Andre Berndt(Correspondence, berndtuw@uw.edu)
Funding
1F31DA056121-01A1
UW ISCRM Graduate Fellowship
Brain Research Foundation
UW Royalty Research Fund
UW ISCRM IPA
NIGMS R01 GM139850-01
P30 DA048736-01-Pilot
NIMH RF1MH130391
NINDS U01NS128537
NIDA R21DA051193
McKnight Foundation’s Technologies in Neuroscience Award
National Science Foundation DGE-2140004
Herbold Foundation
Biological Mechanisms of Healthy Aging Training Grant