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Correlation between actual survival and Tokuhashi and tomita scores in spine metastases

posted on 07.06.2022, 09:54 authored by Alexandre Henrique Silveira Bechara, André Frazão Rosa, Marcelo Ítalo Risso Neto, Marcos Antônio Tebet, Ivan Guidolin Veiga, Wagner Pasqualini, Paulo Tadeu Maia Cavali, Elcio Landim


To evaluate the accuracy of the scores of Tokuhashi and Tomita and the actual survival of patients with vertebral metastases.


A retrospective assessment of 45 patients with spinal metastases. Thirty-one patients underwent surgical treatment and adjuvant therapy and 14 received conservative treatment (chemotherapy/radiotherapy) or palliative/supportive, depending on the scores of Tokuhashi and Tomita.


In the study, 80% of patients were female and the mean age was 57.8 years (SD=11.3 years). The most frequent primary tumors were breast and prostate (68.9%). The accuracy of Tokuhashi scale was 53.4% and the Tomita, 64.5%. The concentration of Tomita range of correct classification was in the category of survival > 12 months (57.8%), while the Tokuhashi scale presented some adjustment in the other categories, < 6 months (15.6%) and 6 to 12 months (2.2%). The histological type of the primary tumor was the only variable that statistically influenced the survival time of patients (p<0.001), and patients with lung or liver tumor (most aggressive) presented a risk of death 9.89 times higher than patients with primary tumors of breast or prostate (less aggressive) (95% CI: 3.10 to 31.57).


The Tokuhashi and Tomita scores showed good accuracy with respect to the actual survival of patients with tumor metastasis in the spine.