ol5b02940_si_001.cif (294.53 kB)

Copper(I)-Catalyzed Intramolecular Trifluoromethylation of Methylenecyclopropanes

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posted on 18.12.2015, 00:00 by Zi-Zhong Zhu, Kai Chen, Liu-Zhu Yu, Xiang-Ying Tang, Min Shi
Copper­(I)-catalyzed intramolecular trifluoromethylation of methylene­cyclopropanes has been developed to produce a variety of CF3-substituted dihydro­naphthalenes in moderate to good yields, relying on the construction of C­(sp2)–CF3 bonds under mild conditions. The reactions proceed through a radical process under copper­(I) catalysis with a good compatibility for the functional group.