posted on 2025-06-23, 23:28authored byWouter VisserWouter Visser, Walther N.M. Klerx, Hans Cremers, Daan Lensen, Liesbeth Dings, Roelina Hoving, Wilbert de Ruijter, Karin Boer, Naomi Weibolt, Max J. van Alphen, Irina Stepanov, Reinskje Talhout
<p dir="ltr">[13C]-isotope labeled sugars were added to cigarettes. Different concentrations, sugars (fructose, glucose, sucrose, and a mixture) were tested with eight cigarette brands, with different design characteristics such as length and filter ventilation and sugar content. Cigarettes were machine-smoked (using ISO and WHO Intense regimes), and the resulting samples were subjected to untargeted and targeted analyses (for volatile organic compounds (VOCs), polycyclic aromatic hydrocarbons (PAHs), aldehydes, tobacco-specific nitrosamines (TSNAs) and nicotine).</p>
Funding
NIH/FDA grant R01 DA051005 (RIVM sub-contract P008078601)