Clinical characteristics of the three subjects whose kidney biopsies were used for scRNA-seq.
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posted on 2022-06-03, 17:30 authored by Hemant Suryawanshi, Hua Yang, Michelle Lubetzky, Pavel Morozov, Mila Lagman, Gaurav Thareja, Alicia Alonso, Carol Li, Catherine Snopkowski, Aziz Belkadi, Franco B. Mueller, John R. Lee, Darshana M. Dadhania, Steven P. Salvatore, Surya V. Seshan, Vijay K. Sharma, Karsten Suhre, Manikkam Suthanthiran, Thomas Tuschl, Thangamani MuthukumarClinical characteristics of the three subjects whose kidney biopsies were used for scRNA-seq.
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therefore likely migratory10x chromium platformworsening graft functionselected 3 biopsiesgenerated 7217 highnative kidney biopsyendothelial cell elaborationcell chemoattractant cytokinescontained plasmablast cellsak2 without fibrosiskidney allograft fibroblastsallograft kidneyhigh expressiongraft infiltrative3 individualskidney cortexcell transcriptomicscell rnayield insightsxlink ">tubulointerstitial fibrosistransplant glomerulopathytaking advantagesuccessful treatmentpersistent presencemediated rejectionskey findingsinfiltrating fibroblastsidentical protocolfresh usingeight monthscould pavecomplex heterogeneityalloimmune injuryactive antibody84 months42 months
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