Biomimetic Models of the Active Site of the Metalloenzyme Nitrile Hydratase

2012-09-02T22:25:28Z (GMT) by Dirk Schweitzer

In the interest of a wider dissemination of the knowledge contained therein, the author's PhD Thesis, entitled "Biomimetic Models of the Active Site of the Metalloenzyme Nitrile Hydratase" (University of Washington, Seattle, 2001), is reproduced here. To illustrate the evolution of knowledge, the author's Precandidacy (1998) and General Exam (1999) papers and a poster (2000) are included.

All of the experimental results contained within this PhD thesis have by now been reported in journal articles. However, this thesis provided room for a much more detailed presentation of the experimental results and their discussion and analysis.

{FeNO}6 model compound [chapter 2]: Journal of the American Chemical Society 1998, 120, 10996-10997

Oxygenated Co(III)-thiolate complexes [pages 16-17 & 113-116]: Journal of the American Chemical Society 2000122, 8299-8300

Improved synthesis of tetramethylammonium azide: Croatica Chemica Acta 200174, 415-418

Reactivity as a function of an Et,Pr or Pr,Pr ligand backbone to model the entatic state of an enzymatic active site [chapter 3]: Inorganic Chemistry 2002, 41, 3128-3136

Fe(III) complexes of an (Namide)2(Sthiolate)2 ligand [chapter 4]: Inorganic Chemistry 2008, 47, 11228-11236