Association of SNPs with blood pressure traits (SBP, DBP and hypertension) among all individuals with African-American ancestry.
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posted on 2021-11-18, 18:50 authored by Harpreet Kaur, Dana C. Crawford, Jingjing Liang, Penelope Benchek, Xiaofeng Zhu, Asha R. Kallianpur, William S. BushAssociation of SNPs with blood pressure traits (SBP, DBP and hypertension) among all individuals with African-American ancestry.
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estimate odds ratiosdiastolic blood pressurecoronary artery diseasecoefficient estimates differbody mass indexblood pressure traitsanalyzed genotype data30 ≥ 59systolic blood pressurevariant rs17080093 associatedsnp rs1530440 associatedidentified loci associatedwide association studieshypertension definition describedadditional genetic studiesamong younger individuals≥ 60 yearsamong individuals older0015 ), howeveryounger individuals βlarge aa cohortxlink "> hypertensionyounger women βdbp respectively ).bmi ), howevereuropean hypertension associationsyounger individualsxlink ">60 yearsyounger womensystolic hypertensionolder womenamong midentire cohortdbp ),rs1361831 associatedhypertension riskwithin womensbp ),jnc ).534 ).050 ).027 ).012 ).011 ).performed usinghigher riskfound rs880315findings suggestevaluate associationsethnic groupsdbp measurementsclinical confoundersbp cohortsalso performedalso conductedafrican americansaa population
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