Anatomy of the left ventricle in aortic stenosis and systemic hypertension

Anatomy of the left ventricle (LV) of 109 cardiac magnetic resonance datasets from 91 participants (18 subjects with aortic stenosis had follow-up data after surgical aortic valve replacement). Full details in Differentiating Left Ventricular Remodeling in Aortic Stenosis From Systemic Hypertension (please cite this reference if using this data)

The LV end diastolic anatomy was reconstructed from the contours using high order interpolation meshes as described in our previous work. The 109 meshes were then spatially aligned by their centre of mass, and by an orientation defined by their basal plane and the left to right direction set by the centre of mass of the LV and right ventricle. A statistical shape model was then built with a principal component analysis (PCA), finding the modes of anatomical variation of this cohort.

Data shared contains:

1. AtlasMeshData.zip, where each case of ID "xxx" has

1.1 Maskxxx.gipl: The mask of the left ventricular (LV) myocardium and right ventricular blood pool from the short axis magnetic resonance image in end diastole

1.2 Maskxxx_mesh files (.exelem and .exnode): the cubic Hermite mesh that was personalised to the anatomy of the left ventricle

1.3 Image_Maskxxx_mesh.jpg: image of the overlay between the fitted mesh and the mask of the LV myocardium

1.4 Image_Initialization.jpg: image of the overlay between the template LV mesh used for personalization and the mask of the LV myocardium

1.5 ImageDistances2ClosestPointMaskxxx_meshxxxxxxxxxx.jpg: image of the distances between the LV mesh and the mask of the LV myocardium (xxxxxxxxxx is a digit encoding for the time when the image was generated)

1.6 PersonalizationReportMaskxxx.txt: file with metrics of mesh fitting accuracy and quality

1.7 GeometricalMetrics.mat: file with metrics of mesh geometry

2. VTKmeshesAlignedDofs.zip: the collection of all the LV shapes in VTK format, after correction of centre of mass and circumferential orientation.

3. AtlasModesAS_s4_c5.pdf: illustration of all the 18 first modes of anatomical variation, together with the box-plot of the differences between experimental groups.