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Download fileText S1 - An “Escape Clock” for Estimating the Turnover of SIV DNA in Resting CD4+ T Cells
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posted on 2012-04-05, 01:51 authored by Jeanette Reece, Janka Petravic, Mehala Balamurali, Liyen Loh, Shayarana Gooneratne, Rob De Rose, Stephen J. Kent, Miles P. DavenportEstimate of half-life of resting infected CD4+ T cells when fW≠fE. We derive the extended model where the rates of infected cells becoming latent differ between cells infected with WT and EM and we show that the negative correlation between half-life of latently infected cells and chronic viral load is preserved in the 2-parameter fit.
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