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Text S1 - An “Escape Clock” for Estimating the Turnover of SIV DNA in Resting CD4+ T Cells

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posted on 2012-04-05, 01:51 authored by Jeanette Reece, Janka Petravic, Mehala Balamurali, Liyen Loh, Shayarana Gooneratne, Rob De Rose, Stephen J. Kent, Miles P. Davenport

Estimate of half-life of resting infected CD4+ T cells when fWfE. We derive the extended model where the rates of infected cells becoming latent differ between cells infected with WT and EM and we show that the negative correlation between half-life of latently infected cells and chronic viral load is preserved in the 2-parameter fit.

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