Age- and Sex-Specific Cerebral Blood Flow Atlases Across the Lifespan

All data are provided in NIfTI format, registered to the MNI reference space, with an isotropic resolution of 1.0 mm³. The dataset is organized into two subfolders: “CBF-atlases”, which contains the mean and standard deviation maps of the age- and sex-specific CBF atlases (CBF_[age group]_[sex]_[mean or std].nii.gz, units: ml/100g/min), and “T1w-template”, which includes the corresponding age-specific T1-weighted structural templates (T1w-template-[age group]-brain.nii.gz). The age groups include CH (children), YO (youth), YA (young adults), MA (middle-aged adults), and OA (older adults), while the sex categories consist of Male, Female, and All (combined Male and Female). All images are saved with floating-point values. The original datasets used for atlas generation are available from the corresponding author upon reasonable request.

In addition to the age-specific templates, we have generated a common template that serves as a central reference across all age groups. This template was created by applying the same methodology used for the age-specific templates but using the generated age-specific templates as inputs instead of individual T1 images. The common T1w template is publicly available in “T1w-template” folder with name of [T1w-template-Allage-brain.nii.gz]. and the common CBF atlases are publicly available in “CBF-atlases” folder with name of [CBF_Allage_mean.nii.gz].