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Additional file 3 of Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genes

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posted on 15.10.2020 by Charles E. Mordaunt, Julia M. Jianu, Benjamin I. Laufer, Yihui Zhu, Hyeyeon Hwang, Keith W. Dunaway, Kelly M. Bakulski, Jason I. Feinberg, Heather E. Volk, Kristen Lyall, Lisa A. Croen, Craig J. Newschaffer, Sally Ozonoff, Irva Hertz-Picciotto, M. Daniele Fallin, Rebecca J. Schmidt, Janine M. LaSalle
Additional file 3: Table S25. DMB gene functional enrichment for all comparisons. Table S26. DMR gene functional enrichment for all comparisons. Table S27. DMR gene functional enrichment for all comparisons with conservative mapping. Table S28. X-linked gene functional enrichment. Table S29. DMR gene ASD study enrichment for all comparisons. Table S30. DMR gene ASD study enrichment for all comparisons with conservative mapping. Table S31. Histone PTM and chromatin state enrichment for all, autosomal, and X-linked discovery males DMRs. Table S32. Histone PTM and chromatin state enrichment for all, autosomal, and X-linked discovery females DMRs. Table S33. Histone PTM and chromatin state enrichment for all, autosomal, and X-linked replication males DMRs. Table S34. Histone PTM and chromatin state enrichment for all, autosomal, and X-linked replication females DMRs. Table S35. CpG context enrichment for all, autosomal, and X-linked DMRs from all comparisons. Table S36. Transcription factor motif enrichment for all, autosomal, and X-linked DMRs from all comparisons. Table S37. Fetal Brain ChromHMM enrichment for top transcription factor motifs. Table S38. Post hoc power analysis.

Funding

National Institute of Environmental Health Sciences National Institute of Child Health and Human Development Environmental Protection Agency (US) Autism Speaks Canadian Institutes of Health

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