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Additional file 1 of Intercellular transfer of exosomal wild type EGFR triggers osimertinib resistance in non-small cell lung cancer

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posted on 19.01.2021, 04:38 by Shaocong Wu, Min Luo, Kenneth K. W. To, Jianye Zhang, Chaoyue Su, Hong Zhang, Sainan An, Fang Wang, Da Chen, Liwu Fu
Additional file 1: Figure S1. NSCLC cells harboring wtEGFR confer osimertinib resistance to sensitive mutEGFR cancer cells in vitro. Figure S2. Exosomal wtEGFR protein can be uptake by mutEGFR NSCLC cells via Clathrin. Figure S3. Osimertinib promotes the release of exosomes via RAB17. Table S1. shRNAs for RAB17, Caveolin-1, Clathrin and RAB27A. Table S2. Sequencing primers for EGFR mutation. Table S3. qPCR primers for screening and validation

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National Major Science and Technology Projects of China National Natural Science Foundation of China (CN)

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