A new insecticidal sesquiterpene from a mangrove endophytic fungus <i>Aspergillus</i> strain sp. GXNU R1
dataset
posted on 2025-04-04, 21:20 authored by Xiongtao Yu, Meijing Tan, Xianglong Bo, Zhifan Lin, Jinwei Chen, Xishan Huang, Jiguo Huang<p>An undescribed sesquiterpene guxinusocapsa A (<b>1</b>), featuring a unique 5/7/6 tricyclic skeleton, and three known compounds (<b>2-4</b>) was isolated from the mangrove endophytic fungus <i>Aspergillus</i> sp. GXNU R1. These isolates were established primarily through NMR data analysis. The new structure’s absolute configuration of <b>1</b> was identified by its single-crystal X-ray diffraction analysis. Compound <b>1</b> showed strong activity towards the Asian citrus psyllid (<i>Diaphorina citri</i>) with 95% lethal at 1000 mg/kg.</p>
Funding
This work was financially supported by the Education Department of Guangdong Province (2024GCZX011); the National Natural Science Foundation of China (42066005); the Natural Science Foundation of Guangxi Province (2020JJA150036); Guangxi Science and Technology Base Special Talents (2019AC20095).
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