figshare
Browse
456553_sm1.docx (119.75 kB)

Supplementary Material for: ANCA Associated Vasculitis Secondary to Levamisole-Adultered Cocaine with Associated Membranous Nephropathy: A Case Series

Download (119.75 kB)
dataset
posted on 2017-01-27, 10:25 authored by Collister D., Sathianathan C., Ryz K., Karpinski M., Bernstein K., Gibson I.W.

Background: Cocaine is a risk factor for acute kidney injury and chronic kidney disease with progression to end-stage renal disease. Levamisole is an adulterant that is added to cocaine to enhance its euphoric effects. Levamisole-adulterated cocaine (LAC) is associated with the distinct clinical syndromes of agranulocytosis, leukocytoclastic vasculitis, cocaine-induced midline destructive lesions (CIMDL), and ANCA-associated vasculitis (AAV) with pauci-immune necrotizing glomerulonephritis. Methods: We reviewed all cases of AAV secondary to LAC at our institution. Results: We report 3 cases of AAV secondary to LAC and associated membranous nephropathy (MN). The first and second cases are concurrent AAV secondary to LAC and associated MN while the third case involves the development of MN after AAV secondary to LAC. Conclusions: Clinicians should be aware of this novel association of LAC with MN.

History

Usage metrics

    American Journal of Nephrology

    Categories

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC