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A new sesquiterpenoid quinone with cytotoxicity from Abelmoschus sagittifolius

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posted on 2015-07-27, 00:00 authored by Hai-Feng Wu, Xu-dong Xu, De-Li Chen, Xiao-Po Zhang, Guo-Xu Ma, Jun-Shan Yang

A new sesquiterpenoid quinone, Acyl hibiscone B (1), together with five known compounds, (R)-lasiodiplodin (2), (R)-de-O-methyllasiodiplodin, (3) dibutyl phthalate (4), (R)-9-phenylnonan-2-ol (5) and hibiscone B (6), was obtained from the stem tuber of Abelmoschus sagittifolius. The structure of compound 1 was elucidated by analysing its 1H and 13C NMR, 1H–1H COSY, HSQC, HMBC, NOESY and HR-ESI-MS values. Compound 1 showed significant cytotoxicity against Hela and HepG-2 human cancer cell lines.

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