<i>N</i>‑Heterocyclic Carbene Catalyzed Oxidative Coupling of Aldehydes with Carbodiimides under Aerobic Conditions: Efficient Synthesis of <i>N</i>‑Acylureas
2013-05-03T00:00:00Z (GMT) by
The oxidative coupling reaction of aldehydes with <i>N,N</i>′-disubstituted carbodiimides catalyzed by <i>N</i>-heterocyclic carbenes under aerobic conditions has been achieved. This reaction gives the corresponding <i>N</i>-acylurea derivatives in good to high yields. Various kinds of aldehydes including aliphatic ones and carbodiimides are applicable to this reaction.