pone.0180276.g006.tif (488.64 kB)
In vitro gene silencing.
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posted on 2017-07-03, 17:39 authored by Bo Li, Wanrong Guo, Fan Zhang, Meiyan Liu, Shang Wang, Zhonghua Liu, Shuanglin Xiang, Youlin ZengSilencing of a luciferase reporter protein in HEK293(A), PC-3(B), Mat(C) cells were conducted with the liposome/siRNA complexes (Ara-DiC12MA, Ara-DiC14MA, Ara-DiC16MA, Ara-DiC18MA). The mean luciferase activity was represented by relative light unit and was calculated from three different measurements. Statistical differences from the Lipo2000 are labelled * P < 0.05, ** P < 0.005 and *** P< 0.001.
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plasmid DNAζ- potentialsAra-DiC 16MAalkane chainsPCAFMnear-spherical shapeDLSMat cellsL-arabinose-based cationic glycolipidscationic lipidstransfer efficiencygene deliveryparticle sizesHEKuptake capabilitygene delivery systemsAra-DiC 16MA liposomesAra-DiC 14MALipofectamine 2000.pDNAsiRNAcell transfectionAra-DiC 18MAforce microscopyAra-DiC 12MA Ara-DiC 14MA Ara-DiC 16MAAra-DiC 16MA liposometransfection efficacyquaternary ammonium
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