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hoxd4a is required for hemangioblast formation.

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posted on 2013-03-16, 07:35 authored by Aseervatham Anusha Amali, Lawrence Sie, Christoph Winkler, Mark Featherstone

(A,B) Normal expression at 13 hpf of posterior hemangioblast markers scl1 (A) and lmo2 (B) in the PLM. (C,D) Expression of these markers is greatly reduced in hoxd4a morphants, but is rescued by co-injection of capped mRNA for hoxd4a (E,F). Ratios indicate the fraction of embryos showing the presented phenotype. Anterior is to the left. A, C and E are dorsal views of flat-mounted specimens while B, D and F are lateral views. Scale bars equal 100 µm. A is at a lower magnification than C and E.

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