(+)-Vitisin A (Vt-A) suppressed RANKL-induced expression of β3 integrin, OC-STAMP, MMP-9 and cathepsin K in RAW264.7 cells.

The relative protein levels were measured by western blot and normalized to β-actin. Data represent the mean ± SEM of at least three independent experiments. *p<0.05, **p<0.01 and ***p< 0.001, different from values after stimulated with RANKL alone.