Validation of the hit compounds using <i>Brugia pahangi</i> adult female worms.

<p>Chemical structures were obtained from <a href="http://www.chemspider.com" target="_blank">www.chemspider.com</a>. The IC<sub>50</sub> for each of the compounds in human fibroblasts (MRC5) is shown in the last column [<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0004401#pntd.0004401.ref026" target="_blank">26</a>]. The IC<sub>50</sub> of Geldanamycin against different human cell lines is a consensus of multiple data available in the literature (<a href="http://www.medchemexpress.com/Geldanamycin.html" target="_blank">www.medchemexpress.com/Geldanamycin.html</a>).</p>