Two computational approaches for determining the 3D structure of genomic domains and genomes.

2013-02-20T16:45:08Z (GMT) by Marc A. Marti-Renom Leonid A. Mirny
<p>(A) The first approach uses polymer models to simulate relevant interactions (both physical and biological) that explain experimental observations. (B) The second approach integrates diverse experimental observations to model a conformational ensemble that satisfies the experimental observations.</p>