Table_2.xls (9.5 kB)
The top SNPs in each of the 9 sub-blocks in the UGT1A gene region (see Figure 2).
dataset
posted on 2013-02-20, 06:36 authored by Juulia Jylhävä, Leo-Pekka Lyytikäinen, Mika Kähönen, Nina Hutri-Kähönen, Johannes Kettunen, Jorma Viikari, Olli T. Raitakari, Terho Lehtimäki, Mikko HurmeThe four SNPs that are associated most significantly with serum cf-DNA levels are in sub-block 8.
†For each SNP, the ancestral allele was modelled, and the β coefficient represents the change in cf-DNA level (µg/ml) with one additional copy of the ancestral allele.
*Adjusted for age, sex, BMI and genetic East-West stratification in the Finnish population.
Abbreviations: SNP, single nucleotide polymorphism; Chr, chromosome; bp, base pairs; MAF, minor allele frequency; S.E., standard error.